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Interferon-gamma.

E De Maeyer·J De Maeyer-Guignard
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Abstract

During the past year, the most striking progress in our understanding of interferon-gamma has been made in the elucidation of the three-dimensional structure of the molecule and in the analysis of the molecular structure and the functional domains of the interferon-gamma receptor. A greater insight into the molecular mechanisms of gene activation by interferon-gamma has been gained, and the immunoregulatory role of interferon-gamma has been better defined in studies dealing with its effects on B-cell function and with its production by the various T-cell subsets. Finally, the effects of interferon-gamma on intracellular parasites is an important aspect of interferon-gamma activity that is giving rise to several clinical trials.

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AnimalsB-LymphocytesBase SequenceConsensus SequenceCytokinesHumansInterferon-gammaMolecular Sequence DataReceptors, InterferonStructure-Activity RelationshipT-Lymphocytes, Helper-InducerJournal ArticleReview

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BibTeXRIS

E De Maeyer, J De Maeyer-Guignard. 1992. Interferon-gamma.. https://doi.org/10.1016/0952-7915(92)90083-q

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