PubMed · 1421038
Current problems in organ transplantation.
Abstract
Organ transplantation has evolved over the past 30 years, although 'new' and 'old' problems remain unsolved, which from a personal point of view, might be summarized as: i) the transfusion effect; ii) HLA matching and pre-graft sensitization of the potential recipient; iii) immunosuppressive drugs; iv) the pathogenesis of chronic rejection; v) infections; vi) de novo cancers. The aim is to attain a state of specific immunological tolerance without the use of immunosuppressive drugs.
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B Charpentier. 1992. Current problems in organ transplantation.. https://doi.org/10.1016/0753-3322(92)90274-b
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