PubMed · 14249625
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J TORRESANI, A JOBIN, R DEVIN, E HENRY, A JOUVE. 1964. [ASSISTED CIRCULATION].. https://pubmed.ncbi.nlm.nih.gov/14249625/
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With the increasing incidence of congestive heart failure and limited numbers of donor hearts for transplantation, mechanical circulatory support devices are being used with greater frequency in Canada. The indications for device use, types of available pumps and centres performing these procedures are presented. A review of the results of use of these devices in Canada indicates that they may be a reasonable alternative for patients who might otherwise die without intervention. The cost implications of more widespread use of these pumps are not insignificant and must be compared with other life-saving technologies.
Congestive heart failure remains a leading cause of morbidity and mortality in the United States, and alternatives to heart transplantation are urgently required. Mechanical circulatory support by ventricular assist devices and total artificial hearts have the potential to provide an alternative to heart transplantation if a small, durable, biocompatible, and totally implantable system is available. In this article, current technologies for mechanical circulatory support by implantable devices are reviewed and the current status and future prospects of the CorAide and MagScrew technologies, which have been developed and tested at the Cleveland Clinic Foundation, are presented.
Flow visualization analysis was applied to the Baylor/Miwatec centrifugal artificial heart to evaluate its fluid dynamic characteristics regarding antithrombogenicity. An eccentric vortex was found both in the upper and the lower gaps of the impeller, which is supposed to be caused by the eccentric inlet port. Therefore, one-way flow toward the outlet is formed and washes the pivot. The combination of an eccentric vortex and a pivot bearing that is washed is unique to the Baylor/Miwatec pump. For the male pivots exposed to periodic wash, the minimum shear rate around the bottom pivot was estimated to be 650/s, which is higher than the threshold for thrombus formation shown by other studies. The wall shear rate at the impeller bottom surface was found to be larger in the top contact mode than in the bottom contact mode.