PubMed · 14250105
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I GOTTFRIED, S GOLDBERG, H LEWENTHAL. 1965-03-13. RAPID SCREENING TEST FOR ADRENAL CORTICAL FUNCTION.. https://doi.org/10.1016/s0140-6736(65)91193-1
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Most chromosomal trisomies lead to miscarriages. In all trisomies, trisomy 1 is the most rare case. We herein present a patient who demonstrated a gestational sac and a yolk sac on transvaginal ultrasound. However, at 53 days of gestation, the pregnancy was lost with a diagnosis of a blighted ovum. A D&C was recommended and performed. A cytogenetic analysis from chorionic villi demonstrated a 47,XX,+1 chromosome complement in all 100 cells. Regarding full trisomy 1, there has only been one case report of a preembryo and two case reports in a clinically recognized pregnancy to date.
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