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INDOLE COMPOUNDS: ISOLATION FROM PINEAL TISSUE.

W M MCISAAC·G FARRELL·R G TABORSKY·A N TAYLOR
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Abstract

Five indole compounds have been isolated from bovine pineal tissue and characterized as 5-methoxytryptophol, N-acetyl-5-methoxytryptamine (melatonin), 5-hydroxytryptophol, 5-methoxyindole-3-acetic acid, and 5-hydroxyindole-3-acetic acid. Pineal hydroxyindole-O-methyltransferase, with S-adenosylmethionine, converts 5-hydroxytryptophol to 5-methoxytryptophol.

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AnimalsCattleChemical PhenomenaChemistryChromatographyElectrophoresisHydroxyindoleacetic AcidIndoleacetic AcidsIndolesMelatoninPineal GlandResearchS-AdenosylmethionineSpectrum AnalysisTransferasesTritiumCATTLECHEMISTRYCHROMATOGRAPHYELECTROPHORESISEXPERIMENTAL LAB STUDYINDOLEACETIC ACIDINDOLESPINEAL BODYSPECTRUM ANALYSISTRANSFERASESTRITIUMJournal Article

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W M MCISAAC, G FARRELL, R G TABORSKY, A N TAYLOR. 1965-04-02. INDOLE COMPOUNDS: ISOLATION FROM PINEAL TISSUE.. https://doi.org/10.1126/science.148.3666.102

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