Transgenic mice in carcinogenicity testing.

R Griesemer; R Tennant

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PubMed · 1428092

Transgenic mice in carcinogenicity testing.

R Griesemer·R Tennant

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Abstract

The biological effects of the expression of single genes can be evaluated in transgenic animals. Transgenic techniques have been used to investigate a wide variety of biomedical topics, including the consequences of oncogene expression, but their use in carcinogenicity testing is just beginning. Probable future developments involving transgenic animals are new short-term assays for carcinogenicity in vivo and methods for detecting and characterizing the critical genotoxic events in carcinogenesis.

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Animals Carcinogenicity Tests Carcinogens Mice Mice, Transgenic Neoplasms, Experimental Journal Article Review

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R Griesemer, R Tennant. 1992. Transgenic mice in carcinogenicity testing.. https://pubmed.ncbi.nlm.nih.gov/1428092/

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