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TETRACYCLINE: EFFECT ON OSTEOGENESIS IN VITRO.

L SAXEN
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Abstract

Tetracycline hydrochloride added to cultures of rudiments of embryonic bone in a concentration of 1 microgram per milliliter prevents mineralization of the bones and is found throughout the calcified zones. The inhibition is reversible; upon transfer of a treated culture to a normal medium, mineralization proceeds normally but maldeveloped bones result.

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AnimalsBone DevelopmentBone and BonesCalcification, PhysiologicEmbryologyFluorescenceIn Vitro TechniquesMiceOsteogenesisPharmacologyPhotomicrographyResearchTetracyclineToxicologyBONE DEVELOPMENTCALCIFICATION, PHYSIOLOGICEMBRYOLOGYEXPERIMENTAL LAB STUDYFLUORESCENCEMICEPHARMACOLOGYPHOTOMICROGRAPHYTETRACYCLINETOXICOLOGIC REPORTJournal Article

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BibTeXRIS

L SAXEN. 1965-08-20. TETRACYCLINE: EFFECT ON OSTEOGENESIS IN VITRO.. https://doi.org/10.1126/science.149.3686.870

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