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PubMed · 14504460

Xpd, a structural bridge and a functional link.

Jian Chen·Beat Suter
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Abstract

Xpd, one of nine polypeptide subunits of the general transcription factor TFIIH plays an organizing role in TFIIH assembly. This structural function in protein complex assembly appears to be used by cells in a dynamic way to regulate and co-ordinate the diverse cellular functions of the different sub-complexes in transcription, DNA repair and cell cycle progression.

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DNA HelicasesDNA RepairDNA-Binding ProteinsHumansMacromolecular SubstancesMitosisMutationProtein SubunitsProteinsTranscription Factor TFIIHTranscription FactorsTranscription Factors, TFIITranscription, GeneticXeroderma Pigmentosum Group D ProteinJournal ArticleReview

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Jian Chen, Beat Suter. Xpd, a structural bridge and a functional link.. https://doi.org/10.4161/cc.2.6.558

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