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DNA nanomotor using duplex-quadruplex conformational transition.

Keiichiro Kanatani·Yuji Ochi·Akimitsu Okamoto·Isao Saito
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Abstract

For DNA nanomotor, we synthesized 8-Py-dG and incorporated it into d(T3G2)4 which can form quadruplex. We measured CD spectra for this ODN. The result suggested that this ODN was changed from quadruplex to duplex by the hybridization with the complementary strand. Further, this ODN had a very interesting property of fluorescence. The fluorescent intensity could be controlled whether the complementary strand was existed, or not.

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Base SequenceCircular DichroismDNANanotechnologyNucleic Acid ConformationSpectrometry, FluorescenceJournal Article

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Keiichiro Kanatani, Yuji Ochi, Akimitsu Okamoto, Isao Saito. 2003. DNA nanomotor using duplex-quadruplex conformational transition.. https://doi.org/10.1093/nass%2F3.1.161

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