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Does selection mold molecular networks?

Andreas Wagner
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Abstract

The dissection of molecular networks vital to cellular life can provide important hints about optimal network design principles. However, these hints can become conclusive only if one can determine that natural selection has molded a network's structure. I illustrate the importance of thorough studies of network evolution with two recent examples, one from genome-scale networks, the other from small transcriptional regulation circuits.

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AnimalsEvolution, MolecularHumansModels, GeneticSelection, GeneticJournal ArticleReview

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Andreas Wagner. 2003-09-30. Does selection mold molecular networks?. https://doi.org/10.1126/stke.2003.202.pe41

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