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Chromatin regulation during C. elegans germline development.

Tae Ho Shin·Craig C Mello
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Abstract

Recent studies in Caenorhabditis elegans implicate PcG- and NuRD-like chromatin regulators in the establishment and maintenance of germline-soma distinctions. Somatic cells appear to utilize NuRD-related nucleosome-remodeling factors to overwrite germline-specific chromatin states that are specified through PcG-like activities. The germline, in turn, may rely on an asymmetrically inherited inhibitor to prevent chromatin reorganization that would otherwise erase pluripotency.

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AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChromatinGene Expression Regulation, DevelopmentalGerm CellsNuclear ProteinsJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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Tae Ho Shin, Craig C Mello. 2003. Chromatin regulation during C. elegans germline development.. https://doi.org/10.1016/s0959-437x(03)00109-6

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