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A role for oligonucleotide-based RNA-knock down technologies in functional genomics.

Gabriele Dorn·Jonathan Hall·Dieter Hüsken·Jörg Lange·Pierre Martin·Francois Natt·William L Wishart·Jan Weiler
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Abstract

Functional genomics is inundating the pharmaceutical industry with large numbers of potential gene targets from several sources such as gene expression profiling experiments (DNA microchips, proteomics) or database mining. Oligonucleotide-based RNA-knock down technologies such as antisense or RNA interference can aid in the filtering and prioritization of target candidates in the drug discovery process.

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Drug IndustryGenomicsOligonucleotide Array Sequence AnalysisOligoribonucleotidesRNARNA, Small InterferingJournal Article

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Gabriele Dorn, Jonathan Hall, Dieter Hüsken, Jörg Lange, Pierre Martin, Francois Natt, William L Wishart, Jan Weiler. A role for oligonucleotide-based RNA-knock down technologies in functional genomics.. https://doi.org/10.1081/ncn-120021970

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