Hypertonic saline for cerebral edema.

Alexandros L Georgiadis; José I Suarez

doi:10.1007/s11910-003-0058-1

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Hypertonic saline for cerebral edema.

Alexandros L Georgiadis·José I Suarez

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Abstract

Raised intracranial pressure (ICP) is a major contributor to the mortality of many conditions encountered in a neurologic intensive care unit. Achieving a sustained reduction in ICP in patients with intracranial hypertension remains a challenge. Treatment with hyperosmolar agents is one of the few options that are available, and mannitol is currently the most commonly used agent. However, hypertonic saline solutions have recently emerged as a potentially safer and more efficacious alternative to mannitol.

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Animals Blood-Brain Barrier Brain Edema Cerebrovascular Disorders Humans Hypernatremia Intracranial Pressure Nervous System Diseases Saline Solution, Hypertonic Journal Article Review

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Alexandros L Georgiadis, José I Suarez. 2003. Hypertonic saline for cerebral edema.. https://doi.org/10.1007/s11910-003-0058-1

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