Ran in the spindle checkpoint: a new function for a versatile GTPase.

Hoi-Yeung Li; Kan Cao; Yixian Zheng

doi:10.1016/j.tcb.2003.09.003

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Ran in the spindle checkpoint: a new function for a versatile GTPase.

Hoi-Yeung Li·Kan Cao·Yixian Zheng

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Abstract

The small GTPase Ran has a well-established role in nucleocytoplasmic trafficking. In recent years, the repertoire of Ran has expanded to include regulation of spindle assembly, formation of the nuclear envelope and DNA replication. Now, new studies further extend the role of Ran to regulating the spindle checkpoint during mitosis.

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Animals Cell Cycle Proteins Guanine Nucleotide Exchange Factors Mitosis Models, Biological Nuclear Proteins Signal Transduction Spindle Apparatus Xenopus Xenopus Proteins ran GTP-Binding Protein Journal Article

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Hoi-Yeung Li, Kan Cao, Yixian Zheng. 2003. Ran in the spindle checkpoint: a new function for a versatile GTPase.. https://doi.org/10.1016/j.tcb.2003.09.003

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