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PubMed · 145741

[Development of eczema from the pathophysiological viewpoint].

G Stüttgen
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Arthus ReactionDermatitis, ContactDrug HypersensitivityEczemaHumansHypersensitivityUltraviolet RaysJournal Article

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G Stüttgen. 1977. [Development of eczema from the pathophysiological viewpoint].. https://pubmed.ncbi.nlm.nih.gov/145741/

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Arthus reaction to recombinant hepatitis B virus vaccine.

A severe, local, inflammatory, late-phase reaction accompanied by skin necrosis occurred after an infant was given an intramuscular injection of recombinant hepatitis B virus vaccine. The clinical course and appearance of the rash were typical of an Arthus reaction. Although not identical to this case, prior reported cases of complement-mediated reactions occurring after hepatitis B virus infection or vaccination provide theoretical support for this diagnosis.

Arthus Reaction↗