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PubMed · 14594593

Melanoma-associated leukoderma.

Elizabeth K Hale·Jody W Konstadt
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Abstract

A case is presented of a man with a history of melanoma treated with sentinel lymphadenectomy and interferon therapy, who subsequently developed diffuse hypopigmented patches thought to be consistent with a diagnosis of melanoma-associated leukoderma. Clinically, melanoma-associated leukoderma is a diffuse macular hypomelanosis or depigmentation, which often develops at sites distant to the location of the primary melanoma. The leukoderma may be hypomelanotic and mottled or depigmented and milk-white. Spontaneous repigmentation may occur. A recent study has demonstrated that T cells involved in the destruction of neoplastic melanocytes are identical clones of those that accumulate in melanoma-associated leukoderma.

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HumansHypopigmentationMaleMelanomaMiddle AgedT-LymphocytesCase ReportsJournal Article

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Elizabeth K Hale, Jody W Konstadt. 2003. Melanoma-associated leukoderma.. https://pubmed.ncbi.nlm.nih.gov/14594593/

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