PubMed · 1459692
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M Sanklecha, S Khambadkone, S F Irani. Peripheral exchange transfusions.. https://doi.org/10.1007/bf02833011
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The transfusion of erythrocytes to neonates and premature infants is common and should be minimized through a reduction in the number of blood samples taken for laboratory tests. The risks to patients have been minimized with current blood-banking techniques, although neonates and premature infants may require special consideration. The indications for transfusion of erythrocytes to neonates include the presence of shock, a loss of 10% or more of the blood volume within 72 hours when further blood sampling is expected, a hemoglobin level of less than 130 g/L in neonates with cardio-respiratory disease who require increased oxygen-carrying capacity, and a hemoglobin level of less than 80 to 100 g/L in neonates with tachypnea, tachycardia, recurrent apnea, poor feeding or failure to gain weight. The attending physician should consider these indications along with clinical judgement to ensure safe and effective erythrocyte transfusion.
The preparation of platelet concentrates from "buffy coat" makes it possible to obtain a platelet concentrate with a low leucocyte and erythrocyte content. Concurrently prepared resuspended red cell concentrates "buffy coat" removed have moreover a low leucocyte and thrombocyte content. The mean number of thrombocytes in 1 TU of thrombocyte concentrate was 0.45 +/- 0.2 x 10(11), the leucocyte content was 0.03 +/- 0.03 x 10(9) and the red cell content was 0.8 +/- 0.7 x 10(9). The described method makes it possible to process in a rational manner blood samples into resuspended red cell concentrate a thrombocyte concentrate and plasma content. The administration of transfusion preparations with of preparation of platelet concentrates in common practice.
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