PubMed Health⌕ Search

PubMed · 14607148

Semantic access processing in a supra-modal deficit: a single case study.

Abstract

The case is presented of a semantic dementia patient, who shows a deficit selective for (i) conceptual class (living things), (ii) attribute processing (visual features) and affecting (iii) input-output modalities at the same processing stage (matching stored representation to attributes). The first experimental part aims at exploring the specific stage/process at which semantic knowledge breaks down through multi-modality tasks, devised to tap different levels within the semantic elaboration flow. The second focuses on the differences between category vs. attribute knowledge across various modalities. The core nature of the patient's deficit is investigated through a close comparison of her damage to a specific processing stage across modalities in the light of her class and attribute-specific impairment. The complex pattern of findings is discussed according to current theoretical accounts of semantic memory organization. Finally, the relevance of the adoption of a broad perspective when dealing with semantic memory impairments is highlighted.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Francesca Borgo, Sara Mondini, Patrizia Bisiacchi. 2003. Semantic access processing in a supra-modal deficit: a single case study.. https://doi.org/10.1016/s0278-2626(03)00110-6

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Comparison of endoscopic techniques vs Shouldice and other open nonmesh techniques for inguinal hernia repair: a meta-analysis of randomized controlled trials.

BACKGROUND: We performed a scientific evaluation of the efficacy of different surgical techniques for inginual hernia repair and supported our findings by conducting a systematic review of randomized studies comparing endoscopic with open nonmesh suture techniques. METHODS: After an extensive search of the literature, a total of 27 studies (41 publications) with evidence level lb were identified. These studies randomly compared endoscopic with open nonmesh suturing techniques. The quality of data sufficed to enable a quantitative meta-analysis of various parameters using the original software of the Cochrane Collaboration. Due to its superiority in comparison to other open nonmesh suturing techniques, the Shouldice repair technique was analyzed separately. RESULTS: The systematic comparison of endoscopic techniques with the Shouldice repair showed that these techniques had significant advantages in terms of the following parameters: total morbidity, hematoma, nerve injury, and pain-associated parameters such as time to return to work, and chronic groin pain. The Shouldice operation has the advantages of a shorter operating time and a lower incidence of wound seroma. There was no difference regarding the incidence of major complications, wound infection, testicular atrophy, or hernia recurrence. Open non-Shouldice suturing techniques are associated with higher recurrence rates and more wound infections than endoscopic operations. CONCLUSION: In comparison to open nonmesh suture repair techniques, endoscopic repair techniques have significant advantages in terms of pain-associated parameters. For the revaluation of long-term complications such as hernia recurrence and chronic groin pain, further clinical examination of the existing study collectives is needed.

Atrophy↗

Voxel-based analysis of multiple-system atrophy of cerebellar type: complementary results by combining voxel-based morphometry and voxel-based relaxometry.

Voxel-based relaxometry (VBR) is a novel morphometric method that analyses the relaxation rate R2 derived from multi-echo T2-weighted images on a voxel-by-voxel basis. We used VBR to study the brain morphology of 14 patients suffering from multiple-system atrophy of cerebellar type (MSA-C) and compared the results with those obtained by voxel-based morphometry (VBM) of T1-weighted images. VBR analysis revealed reduction of relaxation rate R2 in the cerebellum and brainstem reflecting infratentorial brain atrophy. The affected regions largely corresponded to those regions in which VBM showed reductions of grey and white matter. In addition, R2 was increased in the putamen, a region in which VBM did not show abnormalities. Our data show that the combination of VBR and VBM provided convergent and complimentary information about the brain morphology of MSA-C.

Atrophy↗