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PubMed · 14607992

Left ventricular hypertrophy: why does it happen?

Gerard M London
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Abstract

Patients with end-stage renal disease (ESRD) have much higher rates of cardiovascular disease than the healthy population. Left ventricular hypertrophy (LVH), in particular, is common in this patient group. The impact of a decline in haemoglobin concentration on left ventricular mass index has been well documented. Partial correction of anaemia with recombinant human erythropoietin (epoetin) treatment has been recognized as a significant step forward in decreasing left ventricular mass and improving cardiovascular morbidity and mortality. However, LVH and cardiac failure in patients with ESRD comprise a complex condition, which is influenced by a number of factors in addition to anaemia. This article examines some of the pathophysiological aspects of LVH in patients with ESRD.

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AnemiaHemodynamicsHumansHypertrophy, Left VentricularKidney Failure, ChronicJournal ArticleReview

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Gerard M London. 2003. Left ventricular hypertrophy: why does it happen?. https://doi.org/10.1093/ndt%2Fgfg1083

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