A label-free multisensing immunosensor based on imaging ellipsometry.

Zhan Hui Wang; Gang Jin

doi:10.1021/ac0347258

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A label-free multisensing immunosensor based on imaging ellipsometry.

Zhan Hui Wang·Gang Jin

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Abstract

An immunosensor based on imaging ellipsometry and its potential applications was demonstrated in this paper. It has been proven a fast, reliable, and convenient method to quantify the thickness distribution of protein layers or detect protein concentration in solution. Combined with a protein chip, the immunosensor was able to detect multiple analytes simultaneously without any labeling. Preliminary results demonstrated how this immunosensor could be used to monitor several independent biospecific binding processes in real-time and in situ conditions.

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Animals Antibodies Biosensing Techniques Cattle Computer Systems Humans Immunoassay Protein Array Analysis Protein Binding Serum Albumin Serum Albumin, Bovine Time Factors Journal Article Research Support, Non-U.S. Gov't

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Zhan Hui Wang, Gang Jin. 2003-11-15. A label-free multisensing immunosensor based on imaging ellipsometry.. https://doi.org/10.1021/ac0347258

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