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Current developments in SELDI affinity technology.

Ning Tang·Pete Tornatore·Scot R Weinberger
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Abstract

The overall history and recent advancements in Surface-Enhanced Laser Desorption/Ionization (SELDI) affinity technology is reviewed. A detailed account of SELDI technology, utilizing Immobilized-Metal Affinity surfaces, pseudo-specific chromatographic surfaces, and biospecific interactive surfaces, is presented with particular emphasis placed upon examination of fundamental characteristics as well as specific applications for each. Finally, a detailed review of the specific use of such affinity surfaces in fundamental aspects of clinical, process, and research proteomics activity is presented.

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Molecular Probe TechniquesMolecular ProbesProtein Array AnalysisProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationJournal ArticleReview

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Ning Tang, Pete Tornatore, Scot R Weinberger. Current developments in SELDI affinity technology.. https://doi.org/10.1002/mas.10066

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