The contact activation proteins: a structure/function overview.

J C Meijers; B A McMullen; B N Bouma

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PubMed · 1462829

The contact activation proteins: a structure/function overview.

J C Meijers·B A McMullen·B N Bouma

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Abstract

In recent years, extensive knowledge has been obtained on the structure/function relationships of blood coagulation proteins. In this overview, we present recent developments on the structure/function relationships of the contact activation proteins: factor XII, high molecular weight kininogen, prekallikrein, and factor XI, with the emphasis on the localization of domains on these proteins that are involved in the interaction with activators, substrates and cofactors.

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Amino Acid Sequence Binding Sites Blood Coagulation Factors Enzyme Activation Factor XI Factor XII Humans Kininogens Models, Structural Molecular Sequence Data Prekallikrein Protein Conformation Journal Article Review

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J C Meijers, B A McMullen, B N Bouma. 1992. The contact activation proteins: a structure/function overview.. https://pubmed.ncbi.nlm.nih.gov/1462829/

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