Rectal primitive neuroectodermal tumor.

Ricardo Drut; Mónica Drut; Carlos Müller; Adriana Marrón

PubMed · 14692190

Rectal primitive neuroectodermal tumor.

Ricardo Drut·Mónica Drut·Carlos Müller·Adriana Marrón

Abstract

We report the clinical, histologic, immunohistochemical, and molecular findings of a Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) localized to the rectum in a 17-year-old boy. Notably the 4.5 x 4 x 4-cm sessile mass was spontaneously eliminated through the anus, producing an episode of hemorrhagic shock. Histologically the tumor presented as a proliferation of membrane CD99-positive, small round cells. EWS/FLI1 chimeric mRNA was demonstrated by nested reverse-transcription polymerase chain reaction (RT-PCR) analysis in the tumor tissue. The patient is alive and well 2 years after initial symptoms. We also review reported cases of ES/PNET of the digestive system.

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12E7 Antigen Adolescent Antigens, CD Biomarkers, Tumor Cell Adhesion Molecules DNA-Binding Proteins Humans Male Neuroectodermal Tumors, Primitive, Peripheral Proto-Oncogene Protein c-fli-1 Rectal Neoplasms Sarcoma, Ewing Trans-Activators Case Reports Journal Article

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Ricardo Drut, Mónica Drut, Carlos Müller, Adriana Marrón. Rectal primitive neuroectodermal tumor.. https://pubmed.ncbi.nlm.nih.gov/14692190/

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