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e-PTFE ventricular shunt catheters.

D J Gower·D Watson·D Harper
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Abstract

The perfect polymer surface for implantation should resist the adhesion of bacteria while producing no reaction in surrounding tissues. Silicone elastomer is a common material used for medical implantation devices. This material is superior to most available for implantation because of its flexibility and low, but detectable, tissue reaction. We have evaluated a flexible, expanded polytetrafluoroethylene (e-PTFE) ventricular catheter for cerebrospinal fluid shunting and have found that although e-PTFE is safe for cerebral implantation, the porosity of the material allows tissue ingrowth that obstructs the lumen. Our limited clinical evaluation of 5-microns internodal distance e-PTFE revealed that this open-cell structure, allowing tissue ingrowth, apparently is a poor candidate to replace silicone elastomer in cerebrospinal fluid shunting devices. However, further investigation may provide a polymer superior to silicone elastomer to create a cerebrospinal fluid shunt.

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AnimalsEquipment DesignHumansHydrocephalusIntracranial PressureMaleMicroscopy, Electron, ScanningPolytetrafluoroethyleneRatsSilicone ElastomersSubarachnoid HemorrhageSurface PropertiesVentriculoperitoneal ShuntComparative StudyJournal Article

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D J Gower, D Watson, D Harper. 1992. e-PTFE ventricular shunt catheters.. https://doi.org/10.1227/00006123-199212000-00024

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