PubMed · 1471375
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W Kirch. 1992-11-25. [The "diagnostic error" concept].. https://pubmed.ncbi.nlm.nih.gov/1471375/
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Epidemiologic surveys reveal a positive correlation between serum cholesterol levels and the incidence of coronary artery disease. Intervention trials demonstrated that a reduction of serum cholesterol by 1% results in a decrease of coronary non-fatal events by 2%. Fatal coronary events remain almost uninfluenced. On the other side, several intervention trials showed an excess mortality from non-cardiac causes in the therapy groups (i.e. malignant tumors, suicides, accidents). Thus, until now no prolongation of life expectancy could be verified by cholesterol lowering measures.