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PubMed · 14737972

[Leukotrienes as inflammation mediators].

Grzegorz Woszczek·Rafał Pawliczak·Marek L Kowalski
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Abstract

Leukotrienes are biologically active metabolites derived from arachidonic acid playing an important role in inflammatory responses. There are two main groups of leukotrienes: dihydroxyleukotrienes (LTB4) and cysteinyl-leukotrienes (LTC4, LTD4, LTE4). By activating specific G-protein coupled receptors, leukotrienes take part in immune responses, like activation and chemotaxis of leukocytes. Several studies have shown that leukotrienes may play a significant role in pathomechanisms of inflammatory diseases of human airways, skin, digestive tract and heart.

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ChemotaxisHumansInflammation MediatorsLeukotriene B4Leukotriene C4Leukotriene D4Leukotriene E4LeukotrienesLymphocyte ActivationEnglish AbstractJournal ArticleReview

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Grzegorz Woszczek, Rafał Pawliczak, Marek L Kowalski. 2003. [Leukotrienes as inflammation mediators].. https://pubmed.ncbi.nlm.nih.gov/14737972/

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