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PubMed · 14748543

Why rest stimulates bone formation: a hypothesis based on complex adaptive phenomenon.

Ted S Gross·Sandra L Poliachik·Brandon J Ausk·David A Sanford·Blair A Becker·Sundar Srinivasan
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Abstract

Moderate exercise is an ineffective strategy to build bone mass. The authors present data demonstrating that allowing bone to rest between each load cycle transforms low- and moderate-magnitude mechanical loading into a signal that potently induces bone accretion. They hypothesize that the osteogenic nature of rest-inserted loading arises by enabling osteocytes to communicate as a small world network.

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Adaptation, PhysiologicalExerciseHumansMusculoskeletal Physiological PhenomenaOsteocytesOsteogenesisRestSensitivity and SpecificityStress, MechanicalWeight-BearingComparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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Ted S Gross, Sandra L Poliachik, Brandon J Ausk, David A Sanford, Blair A Becker, Sundar Srinivasan. 2004. Why rest stimulates bone formation: a hypothesis based on complex adaptive phenomenon.. https://doi.org/10.1097/00003677-200401000-00003

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