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Squeezing an egg into a worm: C. elegans embryonic morphogenesis.

A J Piekny·P E Mains
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Abstract

We review key morphogenetic events that occur during Caenorhabditis elegans (www.wormbase.org/) embryogenesis. Morphogenesis transforms tissues from one shape into another through cell migrations and shape changes, often utilizing highly conserved actin-based contractile systems. Three major morphogenetic events occur during C. elegans embryogenesis: (1) dorsal intercalation, during which two rows of dorsal epidermal cells intercalate to form a single row; (2) ventral enclosure, where the dorsally located sheet of epidermal cells stretches to the ventral midline, encasing the embryo within a single epithelial sheet; and (3) elongation, during which actin-mediated contractions within the epithelial sheet lengthens the embryo. Here, we describe the known molecular players involved in each of these processes.

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BibTeXRIS

A J Piekny, P E Mains. 2003-12-18. Squeezing an egg into a worm: C. elegans embryonic morphogenesis.. https://doi.org/10.1100/tsw.2003.123

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