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PubMed · 14755893

Technology evaluation: bevacizumab, Genentech/Roche.

Michael L Salgaller
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Abstract

Bevacizumab, an antivascular endothelial growth factor monoclonal antibody, is being developed by Genentech and Roche as an anti-angiogenesis therapy for the potential treatment of solid tumors. In June 2003, bevacizumab was granted Fast Track status by the FDA for the potential treatment of first-line colorectal cancer. The antibody is currently in phase III trials for non-small-cell lung, colorectal and breast cancers, and in phase II trials for various other solid tumor types.

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Angiogenesis InhibitorsAnimalsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsBevacizumabClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicDrug Screening Assays, AntitumorHumansMiceVascular Endothelial Growth Factor AEvaluation StudyJournal Article

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Michael L Salgaller. 2003. Technology evaluation: bevacizumab, Genentech/Roche.. https://pubmed.ncbi.nlm.nih.gov/14755893/

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