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PubMed · 14758248

Safer sharps.

Martha S Matthews·Plastic Surgery Educational Foundation DATA Committee
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CatheterizationEquipment DesignEquipment SafetyHumansInfectious Disease Transmission, Patient-to-ProfessionalNeedlesNeedlestick InjuriesSurgical InstrumentsSyringesJournal Article

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Martha S Matthews, Plastic Surgery Educational Foundation DATA Committee. 2004. Safer sharps.. https://doi.org/10.1097/01.prs.0000101741.34231.f2

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Immune heparin-induced thrombocytopenia (HIT) is a life-threatening adverse effect of heparin. It can result from any type of heparin exposure and by any route of administration; however only a few cases are reported after exposures to small quantities of heparin from catheter flushes. The major clinical problem associated with HIT is thrombosis. Early detection and institution of alternative, non-heparin anticoagulation are important. We report a patient with HIT associated with use of therapeutic-dose unfractionated heparin in whom immune sensitization to heparin was triggered by two 500-unit exposure to UFH associated with intravascular catheter flushing for antineoplastic chemotherapy in a patient with colon adenocarcinoma.

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