Tumorigenicity testing: past concerns, future problems.

P D Noguchi

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PubMed · 1478354

Tumorigenicity testing: past concerns, future problems.

P D Noguchi

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Abstract

Tumorigenicity testing has been an integral part of cell substrate characterization. With the combination of recombinant technology and traditional cell culture, we have entered an era in which many of the principles developed with vaccine production may need to be modified and new ones developed. Models of tumorigenicity are reviewed in the light of current knowledge; the applicability and necessity of such testing in new areas such as somatic cell therapy will also be presented.

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Animals Biological Products Cell Line Cell Transformation, Neoplastic Disease Models, Animal Humans Neoplasm Transplantation Neoplasms, Experimental Journal Article

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P D Noguchi. 1992. Tumorigenicity testing: past concerns, future problems.. https://pubmed.ncbi.nlm.nih.gov/1478354/

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