PubMed1999
Though there are famous theories of "assorted Qi", "membranous origin", the contribution of Wu Youke's Wen yi lun (On Warm Pestilence) of the theory of " expelling pathogens regardless of hard stool" (EPRHS) is even more important. The main points of this theory includes: it is essential to expel pathogens at an early stage, while for attacking therapy, expelling pathogens with rhubarb is essential. EPRHS elucidates the significance of expelling pathogens in attacking therapy theoretically, and elevates the efficacy clinically with profound influence in later ages. In the past 2 decades, the early application of rhubarb to elevate the therapeutic effect for the treatment of pneumonia, epidemic meningitis, and Bencephalitis even in the absence of hard constipated stool marks the significance of Wu's such theory.