PubMed · 14855834
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W J McLEOD. 1951-05-01. Recent reverses in immunization.. https://pubmed.ncbi.nlm.nih.gov/14855834/
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The state control of the anti-diphtheria serum is a prime example for the efficient cooperation between state authorities, industrials and scientists. The article describes firstly the dynamics of this development and places it in the context of already existing approaches to drugs control. Of special interest are the motives which led the different actors to support the state control of sera. Secondly the reciprocal influences between Ehrlich and the serum producers are analyzed. It is shown that practical problems inspired Ehrlich's theoretical work, which in return led to an improvement of measurement techniques.
The concept of maternal immunization to protect the mother against vaccine-preventable disease and the neonate against illness for the first 3-6 months of life is one that is simple, straightforward and safe. Neonatal immunization is largely unsuccessful due to immaturity of the infant's immune system. Therefore, appropriate maternal immunization and passive transferred antibodies to the fetus can protect the neonate until infant vaccination is more efficacious.