PubMed · 14861512
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W B BEAN, M FRANKLIN, K DAUM. 1951. A note on tryptophane and pellagrous glossitis.. https://pubmed.ncbi.nlm.nih.gov/14861512/
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A 50-year-old man was admitted to our clinic with a complaint of lingual enlargement. Detection of non-caseous epithelioid granuloma on histopathological examination led to a diagnosis of a granulomatous glossitis. Extensive investigation for the presence of associated disorders yielded negative results. Metranidazole and clofazimine were totally ineffective and tetracycline led to a minimal improvement. No associated disorder was detected at a 4-year follow-up examination. The position of granulomatous glossitis within the spectrum of orofacial granulomatous conditions is discussed.
Patients frequently present complaining of tongue abnormalities. Knowledge of normal tongue anaomy an d architecture enable the clinician t odifferentiate variations of normal from abnormal conditions. Many tongue conditions are benign and. require reassurance and explanation, with little to no treatment. Others can signify systemic disorders. Examination of the tongue is an integral part of a complete physical examination. Recognizing the disorders of the tongue that are benign and do not require treatment or further evaluation prevents unnecessary testing for the patient. Careful evaluation of the tongue may provide valuable clues to a systemic disorder.
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