PubMed · 14881595
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1951-12-22. LARGE hernia.. https://pubmed.ncbi.nlm.nih.gov/14881595/
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Optimal treatment of groin hernia is a primary public health concern. The inguinal hernia is associated with dysfunctions of the collagen matrix of genetic or acquired origin. Recurrence rate after hernia surgery without mesh reinforcement is estimated at 10-15%. The use of mesh decreases the risk of recurrence by between 50 and 70%. The open techniques (Lichtenstein and derived) are easy to learn, feasible with local anaesthesia and in outpatient setting but they produce chronic pain and sexual disorders. Laparoscopic surgery produces less acute and chronic pain, allows a faster return to the daily activities and allows better cosmetic results. Well codified and taught, the laparoscopy has an important role to play in hernia surgery today as well as in the future.
A counterfeit version of the Ethicon Prolene polypropylene mesh was distributed to hospitals and clinics and unintentionally implanted into patients undergoing tension-free hernia repair. On December 19, 2003, the Food and Drug Administration (FDA) issued a public health web notification indicating that the counterfeit mesh was not sterile or safe to use. To develop safety recommendations for patients with the counterfeit mesh implant, we compared the counterfeit's structural, physical, chemical and mechanical properties with polypropylene meshes previously cleared by FDA. The mesh fibers for all the products tested were found to have similar chemical and physical properties. The mechanical properties were directly related to the knitted structure (loop size, repeat distance, fabric tightness) and the porosity. Extracts from the counterfeit mesh passed cytotoxicity screening tests. The FDA further recommended that if the mesh had been inadvertently implanted, then those patients should be monitored as would be the practice for any patient with an implanted surgical mesh.
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