Cell survival probability under ionizing radiation.

G L Yang

doi:10.1016/0025-5564(92)90029-v

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Cell survival probability under ionizing radiation.

G L Yang

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Abstract

The survival probability of a living cell exposed to ionizing radiation in an experimental setup is derived. The survival of a cell depends on the severity of the radiation damage and efficiency of the cellular repair. The formula of the survival probability is expressed as a function of dose, nonlinear rate of lesion induction, nonlinear rate of cellular repair, and a key experimental parameter--the holding time. The result is an extension of the Markovian dose-response model developed by Yang and Swenberg.

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Animals Cell Survival Models, Biological Models, Statistical Probability Theory Stochastic Processes Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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G L Yang. 1992. Cell survival probability under ionizing radiation.. https://doi.org/10.1016/0025-5564(92)90029-v

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