PubMed · 14902990
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A J KOBAK, L LEVINE. 1952. Interstitial pregnancy developing into the broad ligament.. https://doi.org/10.1016/0002-9378(52)90091-4
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CASE: A unique case of granulosa cell tumor arising in a müllerian cyst of the broad ligament in a 57-year-old woman is presented. The surgically resected unilocular cyst, measuring 9.5 x 9.5 x 6.5 cm3, situated within the right broad ligament. The inner surface of the cyst was lined by a single layer of ciliated columnar cells. Solid cell sheath of the spindled cells were demonstrated in this cystic wall. Immunohistochemically, these spindled cells were diffusely positive for cytokeratin 7, AE1/AE3, vimentin, smooth muscle actin, calretinin and weakly positive for inhibin, but negative for cytokeratin 20, epithelial membrane antigen and CD10. CONCLUSION: Immunohistochemical findings suggested solid cell sheath surrounding the cyst was granulosa cell tumor. Granulosa cell tumor coexisted with müllerian cyst in the current case was recognized a unique histological feature.
A defect in the broad ligament may be congenital or acquired. Due to such a defect, an internal hernia may develop. This usually involves the small bowel. We report a case of internal herniation of the small bowel due to a defect in the broad ligament diagnosed perioperatively. Computerized tomography is helpful in preoperative diagnosis of the condition and should be considered if the condition is suspected clinically. The defect should be closed surgically.
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