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Cerebral perfusion and stroke.

H S Markus
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Abstract

Stroke is a heterogeneous syndrome caused by multiple disease mechanisms, but all result in a disruption of cerebral blood flow with subsequent tissue damage. This review covers the mechanisms responsible for regulation of the normal cerebral circulation, and how they are disrupted in disease states. A central concept in treating patients with acute ischaemic stroke is the existence of an ischaemic penumbra of potentially salvageable tissue, and the evidence for its existence in humans is reviewed.

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Acute DiseaseBrainBrain IschemiaHumansMagnetic Resonance ImagingRegional Blood FlowStrokeTomography, Emission-ComputedTomography, X-Ray ComputedJournal ArticleReview

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H S Markus. 2004. Cerebral perfusion and stroke.. https://doi.org/10.1136/jnnp.2003.025825

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