[Assisted hatching: procedure and effectiveness].

N Frydman

doi:10.1016/s0368-2315(04)96400-9

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[Assisted hatching: procedure and effectiveness].

N Frydman

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Abstract

Assisted hatching (AH) has been proposed to improve the implantation rate in patients with poor prognosis for pregnancy. This systematic review of randomized controlled trials addresses primary outcomes of clinical pregnancy and embryo implantation. Several different methods for AH have been introduced over the years but comparative studies are lacking. AH using laser technology is probably the best technique. Assisted hatching increases the pregnancy and implantation rates significantly in patients with a poor prognosis undergoing IVF or ICSI, particularly in older women. More randomized trials are required to confirm any positive effects on the take-home-baby rate and to compare the different techniques.

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Female Fertilization in Vitro Humans Lasers Pregnancy Prospective Studies Randomized Controlled Trials as Topic Treatment Outcome Zona Pellucida Journal Article Systematic Review

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N Frydman. 2004. [Assisted hatching: procedure and effectiveness].. https://doi.org/10.1016/s0368-2315(04)96400-9

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