Three-dimensional visualization of protein interaction networks.

Kyungsook Han; Yanga Byun

doi:10.1016/s0010-4825(03)00045-3

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Three-dimensional visualization of protein interaction networks.

Kyungsook Han·Yanga Byun

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Abstract

Protein interaction networks provide us with contextual information within which protein function can be interpreted and will assist many biomedical studies. We have developed a new force-directed layout algorithm for visualizing protein interactions in three-dimensional space. Our algorithm divides nodes into three groups based on their interacting properties: bi-connected sub-graph in the center, terminal nodes at the outermost region, and the rest in between them. Experimental results show that our algorithm efficiently generates a clear and aesthetically pleasing drawing of large-scale protein interaction networks and that it is an order of magnitude faster than other force-directed layouts.

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Algorithms Computational Biology Computer Graphics Computer Simulation Imaging, Three-Dimensional Protein Interaction Mapping Journal Article Research Support, Non-U.S. Gov't

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Kyungsook Han, Yanga Byun. 2004. Three-dimensional visualization of protein interaction networks.. https://doi.org/10.1016/s0010-4825(03)00045-3

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