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PubMed · 14974179

[Glimepiride in daily practice].

Mariusz Jasik
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Abstract

Application of the strategies and principles of oral diabetic therapy in type 2 diabetes should be individualized based on the degree of hyperglycemia, insulin deficiency and insulin resistance. This paper presents the evaluation of the new third-generation sulfonylurea compound, glimepiride in daily practice. Glimepiride appears to have several clinical advantages over conventional sulfonylureas: different binding kinetics, advisable cardiovascular effects and beneficial extrapancreatic activity. This may explain the observation that glimepiride provides more stable blood glucose control and lower risk of hypoglycemia over some second-generation sulfonylureas. Glimepiride is safe and well tolerated in patients with type 2 diabetes. Finally, glimepiride also has been shown to be safe and effective in combination with other oral agents or with insulin treatment.

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Diabetes Mellitus, Type 2HumansHypoglycemic AgentsSulfonylurea CompoundsEnglish AbstractJournal ArticleReview

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Mariusz Jasik. 2003. [Glimepiride in daily practice].. https://pubmed.ncbi.nlm.nih.gov/14974179/

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