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Comparative testing of 5 nicotine systems: initial use and preferences.

Nina G Schneider·Richard E Olmstead·Mitchell Nides·Freny Vaghaiwalla Mody·Pamela Otte-Colquette·Kim Doan·Shilpan Patel
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Abstract

OBJECTIVE: To test initial reactions to 5 nicotine treatments (NRTs: 2 and 4 mg gum, inhaler, nasal spray, tablet) in a crossover study (n=41). METHODS: Subjects used each medication on arising (1/2 day) and resumed smoking each afternoon. Subjects rated (individually) and ranked (comparatively) treatments on use, reinforcement, withdrawal, craving, and preferences. RESULTS: Overall preferences: inhaler (49%), 4 mg gum (24%), 2 mg gum (10%), 2 mg tablet (10%), nasal spray (7%). Overall results were consistent with ratings and rankings of individual characteristics of drugs. CONCLUSION: Subjects had varied reactions to NRTs that may affect initiation of cessation.

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Chewing GumCross-Over StudiesDrug Administration RoutesFemaleHumansMaleNicotineSmoking CessationSubstance Withdrawal SyndromeSurveys and QuestionnairesTabletsTobacco Use DisorderClinical TrialComparative StudyJournal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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Nina G Schneider, Richard E Olmstead, Mitchell Nides, Freny Vaghaiwalla Mody, Pamela Otte-Colquette, Kim Doan, Shilpan Patel. Comparative testing of 5 nicotine systems: initial use and preferences.. https://doi.org/10.5993/ajhb.28.1.8

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