Chemical shift anisotropy amplification.

Limin Shao; Charles Crockford; Helen Geen; Giuseppe Grasso; Jeremy J Titman

doi:10.1016/j.jmr.2003.11.005

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Chemical shift anisotropy amplification.

Limin Shao·Charles Crockford·Helen Geen·Giuseppe Grasso·Jeremy J Titman

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Abstract

A new NMR experiment which allows a measurement of the chemical shift anisotropy (CSA) tensor under magic angle spinning (MAS) is described. This correlates a fast MAS spectrum in the omega2 dimension with a sideband pattern in omega1 in which the intensities mimic those for a sample spinning at a fraction of the rate omega r/N, and these sidebands result from an amplification by a factor N of the modulation caused by the CSA. Standard methods can be used to extract the principal tensor components from the omega1 sideband patterns, and the nature of the experiment is such that the use of a large number of t1 increments can be avoided without compromising the resolution of different chemical sites. The new experiment is useful for accurately measuring narrow shift anisotropies.

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Algorithms Anisotropy Carbon Isotopes Computer Simulation Glycine Magnetic Resonance Spectroscopy Methylglucosides Models, Chemical Quality Control Reproducibility of Results Sensitivity and Specificity Signal Processing, Computer-Assisted Spin Labels Comparative Study Evaluation Study Journal Article Research Support, Non-U.S. Gov't Validation Study

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Limin Shao, Charles Crockford, Helen Geen, Giuseppe Grasso, Jeremy J Titman. 2004. Chemical shift anisotropy amplification.. https://doi.org/10.1016/j.jmr.2003.11.005

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