Determining variables for repeat prostate biopsy.

J E Busby; C P Evans

doi:10.1038/sj.pcan.4500708

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Determining variables for repeat prostate biopsy.

J E Busby·C P Evans

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Abstract

During the evaluation of prostate cancer, men who have undergone transrectal ultrasound-guided biopsy with negative results present a dilemma as to what further follow-up is required. Multiple variables have been proposed throughout the literature to improve cancer detection rates not only in initial biopsy results, but also on repeat evaluation. These variables include prostate-specific antigen (PSA) velocity, PSA density, free-percent PSA, and histological findings, each of which may singly or collectively dictate the need for further biopsy. After performing a Medline literature search using specific Medical Subject Headings (prostate biopsy, repeat prostate biopsy, PSA velocity, PSA density, free-percent PSA, prostate inflammation), we critically evaluated pertinent articles. Using this accumulated data and information, we composed an algorithm to assist in the decision process for repeat biopsy.

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Algorithms Biopsy Decision Making Humans Inflammation Male Prostate-Specific Antigen Prostatic Neoplasms Rectum Time Factors Ultrasonography, Interventional Journal Article Review

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J E Busby, C P Evans. 2004. Determining variables for repeat prostate biopsy.. https://doi.org/10.1038/sj.pcan.4500708

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