[Structural-functional units of epidermis].

V V Terskikh; A V Vasil'ev; E A Voroteliak

PubMed · 14994466

[Structural-functional units of epidermis].

V V Terskikh·A V Vasil'ev·E A Voroteliak

Abstract

The available data suggest that epidermis is organized in discrete structural and functional units (SFUs) reproduced both in vivo and in vitro. SFUs are formed in a culture of epidermal keratinocytes by self-organization of the forming cellular elements. SFUs are capable of self-sustaining and form a niche for the stem cells. At the same time, due to the maintained asymmetric kinetics of the stem cell proliferation, SFUs serve as a barrier for their uncontrolled replication.

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Animals Cells, Cultured Epidermal Cells Epidermis Humans Keratinocytes Journal Article Review

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V V Terskikh, A V Vasil'ev, E A Voroteliak. [Structural-functional units of epidermis].. https://pubmed.ncbi.nlm.nih.gov/14994466/

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