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PubMed · 15003210

MicroRNAs: something important between the genes.

Allison C Mallory·Hervé Vaucheret
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Abstract

Non-coding small endogenous RNAs, of 21-24 nucleotides in length, have recently emerged as important regulators of gene expression in both plants and animals. At least three categories of small RNAs exist in plants: short interfering RNAs (siRNAs) deriving from viruses or transgenes and mediating virus resistance or transgene silencing via RNA degradation; siRNAs deriving from transposons or transgene promoters and controlling transposon and transgene silencing probably via chromatin changes; and microRNAs (miRNAs) deriving from intergenic regions of the genome and regulating the expression of endogenous genes either by mRNA cleavage or translational repression. The disruption of miRNA-mediated regulation causes developmental abnormalities in plants, demonstrating that miRNAs play an important role in the regulation of developmental decisions.

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Gene Expression Regulation, PlantGenes, PlantMicroRNAsRNA, Small InterferingJournal ArticleResearch Support, Non-U.S. Gov'tReview

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BibTeXRIS

Allison C Mallory, Hervé Vaucheret. 2004. MicroRNAs: something important between the genes.. https://doi.org/10.1016/j.pbi.2004.01.006

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