PubMed Health⌕ Search

PubMed · 15005513

[Y-chromosome analysis].

Abstract

After initially slow progress in identifying DNA polymorphisms on the non recombining part of the human Y chromosome, a large number of polymorphic markers are now available to define individual or population-specific haplotypes or haplogroups. Among them the Y-chromosomal STRs (Short Tandem Repeats) have been increasingly used over the past few years for the study of human evolution as well as for human identification in forensic case-work and paternity testing. After a brief summary of the features of such markers, this paper deals with some applications of the Y-STR haplotyping.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Christine Keyser-Tracqui, Bertrand Ludes. 2003. [Y-chromosome analysis].. https://pubmed.ncbi.nlm.nih.gov/15005513/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Human populations: houses for spouses.

Patterns of genetic variability in human populations are profoundly influenced by social organisation, including lifestyle, language, religion and social status. A nice illustration is seen among societies that have specific rules about who can marry whom.

Chromosomes, Human, Y↗

Allele and haplotype distribution for 16 Y-STRs (AmpFlSTR Y-filer kit) in the state of Chihuahua at North Center of Mexico.

The AmpFlSTR Y-filer kit, including 16 Y-STRs was analyzed in 326 males from Chihuahua, at North Central, Mexico. Allele frequencies and gene diversity for each locus were estimated. Four allele duplications, namely DYS389II, DYS390, DYS391 and DYS439; and one allele null at DYS448 were observed in the sample. The haplotype diversity was 99.97+/-0.3%. The AMOVA results, including a previous report from West of Mexico (Jalisco), showed that most of the genetic variability between these Mexican populations is attributable to intrapopulational differences (99.87%). This result supports a low-genetic differentiation between males from North and West regions of Mexico.

Chromosomes, Human, Y↗

No signature of Y chromosomal resemblance between possible descendants of the Cimbri in Denmark and Northern Italy.

Two European populations are believed to be related to the ancient Germanic tribe Cimbri: one living in Northern Italy, the other living in Jutland, Denmark. The people called Cimbri are documented in the ancient Roman historical record. Arriving from the far north their movements can be tracked from successive battles with the Romans. The Cimbri finally entered Italy from the northeast and were defeated at Vercellae (present day Vercelli) in 101 BC by Gaius Marius and his professional legions. Classical sources from the first centuries AD relate the homeland of the Cimbri to the coasts around the Elb estuary (northern Germany) or specifically towards the north (Himmerland in northern Jutland). In the alpine parts of Veneto, northeast of the historical battlefield, local traditions dating back to late medieval time, identify a local population as Cimbri living in Terra dei Cimbri. They are considered the descendents of the Germanic combatants that fled the battlefield at Vercelli. As the defeated Cimbri that possibly fled to the mountains of Northern Italy most likely would have been male (warriors), the present study investigated the possible Y chromosomal diversity of the two present populations using microsatellite markers and single nucleotide polymorphisms. While Cimbri from Himmerland resembled their geographical neighbors from Denmark for the Y-chromosome markers, Cimbri from Italy were significantly differentiated both from Cimbri from Himmerland and from Danes. Therefore, we were not able to show any biological relationship for uniparentally transmitted markers.

Chromosomes, Human, Y↗