Mobile elements: drivers of genome evolution.

Haig H Kazazian

doi:10.1126/science.1089670

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Mobile elements: drivers of genome evolution.

Haig H Kazazian

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Abstract

Mobile elements within genomes have driven genome evolution in diverse ways. Particularly in plants and mammals, retrotransposons have accumulated to constitute a large fraction of the genome and have shaped both genes and the entire genome. Although the host can often control their numbers, massive expansions of retrotransposons have been tolerated during evolution. Now mobile elements are becoming useful tools for learning more about genome evolution and gene function.

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Alu Elements Animals DNA Methylation DNA Transposable Elements Evolution, Molecular Genome Genome, Human Humans Long Interspersed Nucleotide Elements RNA, Small Interfering Recombination, Genetic Retroelements Terminal Repeat Sequences Journal Article Research Support, U.S. Gov't, P.H.S.Review

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Haig H Kazazian. 2004-03-12. Mobile elements: drivers of genome evolution.. https://doi.org/10.1126/science.1089670

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