Pathogenic Escherichia coli.

James B Kaper; James P Nataro; Harry L Mobley

doi:10.1038/nrmicro818

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Pathogenic Escherichia coli.

James B Kaper·James P Nataro·Harry L Mobley

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Abstract

Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

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Animals Bacterial Adhesion Diarrhea Escherichia coli Gene Expression Regulation, Bacterial Humans Meningitis, Bacterial Shiga Toxins Urinary Tract Infections Virulence Factors Journal Article Research Support, U.S. Gov't, P.H.S.Review

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James B Kaper, James P Nataro, Harry L Mobley. 2004. Pathogenic Escherichia coli.. https://doi.org/10.1038/nrmicro818

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