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PubMed · 1504627

The MHC: relationship between linkage and function.

J Trowsdale·S H Powis
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Abstract

It is intriguing that several genes with associated functions, including all of class I and class II genes, as well as some genes affecting antigen presentation of both class I and class II pathways, are linked in the MHC. Recent observations have led to speculation that there may be a functional explanation for keeping these related genes together.

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AnimalsAntigensGenetic Diseases, InbornGenetic LinkageHumansMajor Histocompatibility ComplexJournal ArticleReview

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J Trowsdale, S H Powis. 1992. The MHC: relationship between linkage and function.. https://doi.org/10.1016/s0959-437x(05)80163-7

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